Microneedling: A Primer for Dermatologists

Microneedling is a minimally invasive procedure that is becoming widely utilized in dermatology. Microneedles (MNs) are fine, needle-like structures that penetrate the skin. MNs can be used for percutaneous collagen induction (PCI) therapy and to augment transdermal drug delivery. This review is a primer on microneedling for dermatologists. It provides an overview of the history, instruments, principle of PCI, drug delivery mechanism, applications for dermatologic conditions, and adverse effects. For MN applications in dermatology, PubMed database was used to search for studies and search terms included “microneedling” and “percutaneous collagen induction.” Priority was given to studies with human subjects and prospective, randomized trials. Studies demonstrate success with microneedling for skin rejuvenation, acne scars, non-acne scars, acne vulgaris, hyperpigmentation, alopecia, hyperhidrosis, and drug delivery. The procedure is reported to be safe with minimal adverse side effects. As MN use becomes more widespread, it is important to increase the number of randomized, controlled trials to provide further data on the efficacy and safety of microneedling. Kathryn Konicke, Michael Knabel and Edit Olasz* Department of Dermatology, Medical College of Wisconsin, USA Edit Olasz, et al., Journal of Dermatology and Plastic Surgery Remedy Publications LLC. 2017 | Volume 2 | Issue 2 | Article 1014 2 for use by professionals or at home. Major issues with derma rollers are poor regulation of home derma rollers and unsubstantiated claims. Other disadvantages are that they are single use; disposable instruments and those they only allow one fixed needle length [6]. Microneedling pens were developed to overcome variations in pressure and penetration depth that occur with derma rollers. Dermapen was one of the first microneedling pens available. It is an automated micro needling device with 9-12 disposable needles that operate in a stamp-like manner. Disposable needles allow the device to be reusable; therefore it is more economical than derma rollers as it can be used on different patients [7]. There are many more microneedling pens now available and currently in development.